[(cyanocarbonyl)oxy]ethane
Ethyl cyanoformate
CAS: 623-49-4
Molecular Formula: C4H5NO2
[(cyanocarbonyl)oxy]ethane - Names and Identifiers
| Name | Ethyl cyanoformate |
| Synonyms | ETHYL CYANOFORMATE Ethyl cyanoformate ethyl carbonocyanidate Ethyl carbonocyanidoate [(cyanocarbonyl)oxy]ethane Cyanoformic acid ethyl ester CYANOFORMIC ACID ETHYL ESTER |
| CAS | 623-49-4 |
| EINECS | 210-797-9 |
| InChI | InChI=1/C4H5NO2/c1-2-7-4(6)3-5/h2H2,1H3 |
[(cyanocarbonyl)oxy]ethane - Physico-chemical Properties
| Molecular Formula | C4H5NO2 |
| Molar Mass | 99.09 |
| Density | 1.003 g/mL at 25 °C (lit.) |
| Boling Point | 115-116 °C (lit.) |
| Flash Point | 76°F |
| Solubility | Miscible with chloroform and methanol. |
| Vapor Presure | 19mmHg at 25°C |
| Appearance | Liquid |
| Specific Gravity | 1.01 |
| Color | Clear colorless |
| Exposure Limit | NIOSH: IDLH 25 mg/m3 |
| BRN | 635955 |
| Storage Condition | Inert atmosphere,2-8°C |
| Sensitive | Moisture Sensitive |
| Refractive Index | n20/D 1.381(lit.) |
[(cyanocarbonyl)oxy]ethane - Risk and Safety
| Risk Codes | R10 - Flammable R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R34 - Causes burns R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S24/25 - Avoid contact with skin and eyes. S16 - Keep away from sources of ignition. S7/9 - |
| UN IDs | UN 3275 6.1/PG 2 |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10-19-21 |
| TSCA | Yes |
| HS Code | 29269090 |
| Hazard Class | 6.1 |
| Packing Group | II |
[(cyanocarbonyl)oxy]ethane - Reference Information
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| properties | ethyl cyanoformate is a colorless transparent liquid. |
| Application | ethyl cyanoformate is a carboxylic acid ester derivative, which is a very important chemical intermediate, widely used in pharmaceutical, pesticide, chemical and textile fields, can be used for the production of esters, amides and heterocyclic compounds and synthetic drugs, herbicides, fungicides, pesticides, and other chemicals, it can also be used as an intermediate in the synthesis of the anti-infective cefazolin and in the synthesis of tetrazolium acetic acid. |
| synthesis method | The synthesis steps of ethyl cyanoformate are as follows: S1, clean the reactor, add S-1500 of aromatic hydrocarbon solvent to the reactor; S2, add 695kg of ethyl chloroformate and of hydrocyanic acid to the dropper; S3, add 30kg of triethylamine catalyst and 20kg of purified water to the reaction kettle, start the reaction kettle to stir and mix for 15 minutes, then stop the reaction kettle; S4, start the reaction kettle after reducing the temperature in the reaction kettle to 2 ℃, add ethyl chloroformate and hydrocyanic acid Dropwise under low-speed stirring, and control the dropping rate to complete the dropping within 2 hours; S5, continue stirring for 30 minutes after the dropping is completed, crude ethyl cyanoformate is obtained, and then the crude cyanoformate is transferred to a distillation column to perform atmospheric distillation on the crude cyanoformate, and the fraction before 90 ° C is removed to obtain a Colorless fuming fraction at 115-116 ° C, S6, the raw material is subjected to cyanidation reaction and distillation separation of ethyl cyanoformate, and then it is subjected to hydrogen oxidation The catalyst was recovered by sodium phase-separation washing. |
Last Update：2024-04-10 22:29:15
![[(cyanocarbonyl)oxy]ethane](http://res.chembk.com/assets/str/2d/6/62/623-49-4.png)
Supplier List
Spot supply
Product Name: Ethyl cyanoformate Request for quotationCAS: 623-49-4
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Product Name: Ethyl cyanoformate Request for quotation
CAS: 623-49-4
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
CAS: 623-49-4
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Spot supply
Product Name: Ethyl cyanoformate Request for quotationCAS: 623-49-4
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Product Name: Ethyl cyanoformate Request for quotation
CAS: 623-49-4
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
CAS: 623-49-4
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
View History